Basosquamous carcinoma: Is it an aggressive tumor?
- 20 August 2014
- journal article
- Published by Informa UK Limited in Journal of Plastic Surgery and Hand Surgery
- Vol. 49 (2), 107-111
- https://doi.org/10.3109/2000656x.2014.944188
Abstract
Basosquamous carcinoma is a rare cutaneous tumour that is considered an aggressive type of basal cell carcinoma with an increased risk of recurrence and metastases. This impression has been perpetuated in the literature, despite limited scientific data and conflicting results of some authors. This present study was aimed to evaluate the clinical-pathological features of this tumour and follow-up of a series of basosquamous carcinoma. Basosquamous carcinoma patients who underwent surgical excision between January 2000 and February 2012 were analyzed retrospectively. Their medical files were reviewed and the corresponding routinely stained sections (with hematoxylin-eosin) were re-evaluated by two pathologists. Thirty-five patients with basosquamous carcinoma were operated on in this period. Most tumurs were located in the head and neck area (94%), and the mean age of the patients was 69.8 years. Margin involvements were seen in 11 patients (31.4%) and all of them underwent re-excision. There was only one local recurrence. There was neither regional lymph node nor distant metastasis in this series. The recurrence rate of basosquamous carcinoma is found as 4%, lower than that of most other similar studies. Further pathologic studies are needed to better classify basosquamous carcinoma and to increase consistency between the results of studies. Surgical excision and regular follow-up are considered as the treatment of choice.Keywords
This publication has 18 references indexed in Scilit:
- Basosquamous cell carcinoma: a survey of 76 patients and a comparative analysis of basal cell carcinomas and squamous cell carcinomasEuropean Journal Of Dermatology, 2013
- Prise en charge diagnostique et thérapeutique du carcinome épidermoïde cutané (spinocellulaire) et de ses précurseurs. RecommandationsAnnales de Dermatologie et de Vénéréologie, 2009
- Guidelines for the management of basal cell carcinomaBritish Journal of Dermatology, 2008
- Periocular metatypical cell carcinoma: clinicopathologic correlation, management, and follow-up in 35 patientsJournal of Plastic, Reconstructive & Aesthetic Surgery, 2006
- Basosquamous carcinomaCancer, 2005
- What is Basosquamous Carcinoma?Dermatologic Surgery, 2000
- Basosquamous carcinomaCancer, 2000
- Surgical margins for excision of primary cutaneous squamous cell carcinomaJournal of the American Academy of Dermatology, 1992
- Basosquamous cell carcinoma of the skin with metastasesHistopathology, 1988
- Cutaneous Basosquamous Carcinoma of the Head and Neck: A Comparative AnalysisOtolaryngology -- Head and Neck Surgery, 1979