Antiviral Agents Acting as DNA or RNA Chain Terminators
- 1 January 2009
- book chapter
- review article
- Published by Springer Science and Business Media LLC in Handbook of Experimental Pharmacology
- No. 189,p. 53-84
- https://doi.org/10.1007/978-3-540-79086-0_3
Abstract
Nucleoside or nucleotide analogue inhibitors of viral replication almost act as chain terminators during DNA (DNA- and retroviruses) or RNA (RNA viruses) synthesis. Following intracellular phosphorylation, by viral and/or cellular kinases, the 5′-triphosphate...Keywords
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