Strychnine Poisoning: Clinical and Toxicological Observations on a Non-Fatal Case
- 1 January 1986
- journal article
- case report
- Published by Informa UK Limited in Journal of Toxicology: Clinical Toxicology
- Vol. 24 (3), 245-255
- https://doi.org/10.3109/15563658608990462
Abstract
The successful supportive management of an acute strychnine ingestion is described; clinical and biochemical findings are reported. A gas chromatographic assay for serum strychnine has been applied to the analysis of 19 serial blood samples. Four hours post ingestion, the serum strychnine concentration was 1.6 mg/L. This declined with T of 10 hours over a period of 50 hours. First order kinetics are indicated. Management of strychnine poisoning in general is discussed in the light of this case and the limited knowledge of the pharmacokinetics of the alkaloid in man.Keywords
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