Non esterified fatty acids (NEFA) in dairy cattle. A review
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Open Access
- 1 September 2005
- journal article
- review article
- Published by Informa UK Limited in Veterinary Quarterly
- Vol. 27 (3), 117-126
- https://doi.org/10.1080/01652176.2005.9695192
Abstract
The objective of this report is to review the literature on elevated blood concentrations of nonesterified fatty acids (NEFA) before and after parturition in high‐yielding dairy cows. It highlights the factors that influence serum NEFA production and their circulation before and after parturition, such as adaptation for nutrient partitioning for fetal needs, onset of lactogenesis, stress of calving and numerous changes in physiological, metabolic, and endocrine status to accommodate parturition and lactogenesis. The role of NEFA in the liver and peripheral tissues and its toxic effects when in excess are discussed. The cow's adaptive physiologic mechanisms to prevent or decrease excessive values of serum NEFA and preventive and therapeutic interventions to enhance these mechanisms are categorized as natural and artificial antidotes respectively. Feeding systems during the dry period and daily exercise or walking activity which may burn excessive NEFA through β‐oxidation in the muscles are considered as more useful antidotes to managing the NEFA metabolism. This will minimize accumulation of lipids in the liver during early lactation and alleviate the negative effects of plasma NEFA leading to more optimal metabolic health and productivity of dairy cows.Keywords
This publication has 66 references indexed in Scilit:
- Mitochondrial β‐oxidationEuropean Journal of Biochemistry, 2004
- NUTRITIONAL REGULATION OF MILK FAT SYNTHESISAnnual Review of Nutrition, 2003
- Non-esterified fatty acid levels and physical inactivity: the relative importance of low habitual energy expenditure and cardio-respiratory fitnessBritish Journal of Nutrition, 2002
- Regulation of nutrient partitioning during lactation: homeostasis and homeorhesis revisited.Published by CABI Publishing ,2000
- Relations between Plasma Acetate, 3-Hydroxybutyrate, FFA, Glucose Levels and Energy Nutrition in Lactating Dairy Cows.The Journal of Veterinary Medical Science, 1999
- Nutritional Implications of Gastrointestinal and Liver Metabolism in RuminantsNutrition Research Reviews, 1993
- Effects of diet on lipolysis and its regulationProceedings Of The Nutrition Society, 1992
- Relations between plasma non-esterified fatty acid metabolism and body fat mobilization in primiparous lactating goatsBritish Journal of Nutrition, 1989
- Relations between plasma non-esterified fatty acid metabolism and body tissue mobilization during chronic undernutrition in goatsBritish Journal of Nutrition, 1988
- Effects of different energy intakes before and after calving on food intake, performance and blood hormones and metabolites in dairy cowsAnimal Science, 1985