Hydroxylation of 5α-androstane-3β,17β-diol by rat prostate microsomes: Potent inhibition by imidazole-type antimycotic drugs and lack of inhibition by steroid 5α-reductase inhibitors
- 1 August 1992
- journal article
- Published by Elsevier BV in Archives of Biochemistry and Biophysics
- Vol. 296 (2), 366-373
- https://doi.org/10.1016/0003-9861(92)90586-l
Abstract
No abstract availableKeywords
This publication has 42 references indexed in Scilit:
- Pathogenesis and medical treatment of benign prostatic hyperplasiaThe Prostate, 1989
- The dihydrotestosterone (DHT) hypothesis of prostate cancer and its therapeutic implicationsThe Prostate, 1986
- Hydroxylation of [3h]5α-androstane-3β,17β-diol by whole tissue, epithelial cells and fibroblasts from the same hyperplastic human prostateThe Journal of Steroid Biochemistry and Molecular Biology, 1985
- Effects of 6- and 7-hydroxy metabolites of 3β,17β-dihydroxy-5α-androstane on gonadotrophin and prolactin secretion and on sex accessories weight of male ratsThe Journal of Steroid Biochemistry and Molecular Biology, 1983
- Changes in the Metabolism of Dihydrotestosterone in the Hyperplastic Human Prostate*Journal of Clinical Endocrinology & Metabolism, 1983
- Synthesis and androgen effects of 7α, 17β-dihydroxy-5α-androstan-3-one, 5α-androstan-3α,7α,17β-triol and 5α-androstane-3β,7α,17β-triolThe Journal of Steroid Biochemistry and Molecular Biology, 1982
- 5α-Androstane-3β, 17β-diol and 5α-androstane-3β,7α, 17β-triol in the human hyperplastic prostateJournal of Steroid Biochemistry, 1980
- Metabolism of C19-radiosteroids by explants of canine prostate and epididymis with disposition as hydroxylated products: A possible mechanism for androgen inactivationThe Journal of Steroid Biochemistry and Molecular Biology, 1979
- A comparative study of binding, metabolism and endogenous levels of androgens in normal, hyperplastic and carcinomatous human prostateJournal of Steroid Biochemistry, 1979
- Comparison of testosterone, 5α-dihydrotestosterone and 5α-androstane-3β,17β-diol metabolisms in human normal and hyperplastic prostatesThe Journal of Steroid Biochemistry and Molecular Biology, 1978