Interaction of Curare and Related Substances with Acetylcholine Receptor-Like Protein
- 12 June 1959
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 129 (3363), 1613-1614
- https://doi.org/10.1126/science.129.3363.1613
Abstract
Existence of a receptor protein for acetylcholine has been postulated, and the hypothesis has been supported by experiments in intact cells. A protein from electric tissue has now been obtained in solution; there is striking parallelism between the ability of this protein to bind acetylcholine analogs and the effects of such analogs on electrical manifestations of intact electroplax.Keywords
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