Pituitary-Ovarian Responses to Nafarelin Testing in the Polycystic Ovary Syndrome
- 2 March 1989
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 320 (9), 559-565
- https://doi.org/10.1056/nejm198903023200904
Abstract
To investigate the basis of polycystic ovary syndrome, we examined the responses of patients to nafarelin, a specific gonadotropin-releasing-hormone agonist, given to stimulate pituitary and gonadal secretion. We compared 16 normal women in the follicular phase, 5 normal men, 8 women with polycystic ovary syndrome, and 1 woman with polycystic ovary syndrome caused by a 3β-hydroxysteroid dehydrogenase deficiency.This publication has 28 references indexed in Scilit:
- Pathogenesis and Treatment of Polycystic Ovary SyndromeNew England Journal of Medicine, 1988
- The Rapid Ovarian Secretory Response to Pituitary Stimulation by the Gonadotropin-Releasing Hormone Agonist Nafarelin in Sexual Precocity*Journal of Clinical Endocrinology & Metabolism, 1986
- Acute ovarian responses to a long-acting agonist of gonadotropin-releasing hormone in ovulatory women and women with polycystic ovarian diseaseFertility and Sterility, 1985
- Ablation of folliculogenesis in women by a single dose of gonadotropin-releasing hormone agonist: significance of time in cycleFertility and Sterility, 1985
- The Stimulatory and Down-Regulatory Effects of a Gonadotropin-Releasing Hormone Agonist in Man*Journal of Clinical Endocrinology & Metabolism, 1984
- Hirsutism: Implications, etiology, and managementAmerican Journal of Obstetrics and Gynecology, 1981
- Pubertal Presentation of Congenital Δ5–-3β–Hydroxysteroid Dehydrogenase Deficiency*Journal of Clinical Endocrinology & Metabolism, 1980
- Functional Studies of Aromatase Activity in Human Granulosa Cells from Normal and Polycystic Ovaries*Journal of Clinical Endocrinology & Metabolism, 1979
- CONCURRENT 3β-HYDROXYSTEROID DEHYDROGENASE DEFICIENCY IN ADRENAL AND SCLEROCYSTIC OVARYActa Endocrinologica, 1965
- The Polycystic Ovary. III. Steroid Biosynthesis in Normal and Polycystic Ovarian Tissue1Journal of Clinical Endocrinology & Metabolism, 1962