A High-Resolution Microsatellite Map of the Mouse Genome
Open Access
- 1 May 1998
- journal article
- Published by Cold Spring Harbor Laboratory in Genome Research
- Vol. 8 (5), 531-542
- https://doi.org/10.1101/gr.8.5.531
Abstract
The European Collaborative Interspecific Backcross (EUCIB) resource was constructed for the purposes of high-resolution genetic mapping of the mouse genome (Breen et al. 1994). The large Mus spretus/C57BL/6 backcross of 982 progeny has a genetic resolution of 0.3 cM at the 95% confidence level (∼500 kb in the mouse genome). We have used the EUCIB mapping resource to develop a genome-wide high-resolution genetic map incorporating 3368 microsatellites. The microsatellites are distributed among 2302 genetically separated bins with 1.46 markers per bin on average. Average bin separation is 0.61 cM. This high-resolution genetic map will aid the construction of a robust physical map of the mouse genome.Keywords
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