Pre-existing AAV Capsid-specific CD8+ T Cells are Unable to Eliminate AAV-transduced Hepatocytes
Open Access
- 30 April 2007
- journal article
- Published by Elsevier BV in Molecular Therapy
- Vol. 15 (4), 792-800
- https://doi.org/10.1038/sj.mt.6300090
Abstract
No abstract availableKeywords
This publication has 26 references indexed in Scilit:
- Prevention of cytotoxic T lymphocyte responses to factor IX-expressing hepatocytes by gene transfer-induced regulatory T cellsProceedings of the National Academy of Sciences, 2006
- Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune responseNature Medicine, 2006
- New AAV Serotypes May Broaden the Therapeutic Pipeline to Human Gene TherapyMolecular Therapy, 2006
- Identification of mouse AAV capsid-specific CD8+ T cell epitopesMolecular Therapy, 2005
- CD4+CD25+ T Cells Regulate Virus-specific Primary and Memory CD8+ T Cell ResponsesThe Journal of Experimental Medicine, 2003
- A Simian Replication-Defective Adenoviral Recombinant Vaccine to HIV-1 GagPublished by The American Association of Immunologists ,2003
- Sustained high-level expression of human factor IX (hFIX) after liver-targeted delivery of recombinant adeno-associated virus encoding the hFIX gene in rhesus macaquesBlood, 2002
- Sustained phenotypic correction of hemophilia B dogs with a factor IX null mutation by liver-directed gene therapyBlood, 2002
- Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarizationNature Medicine, 1999
- Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectorsProceedings of the National Academy of Sciences, 1997