Potassium Channel Dysfunction in Cerebral Arteries of Insulin-Resistant Rats Is Mediated by Reactive Oxygen Species
- 1 April 2004
- journal article
- research article
- Published by Wolters Kluwer Health in Stroke
- Vol. 35 (4), 964-969
- https://doi.org/10.1161/01.str.0000119753.05670.f1
Abstract
Background and Purpose— Insulin resistance (IR) increases the risk of stroke in humans. One possible underlying factor is cerebrovascular dysfunction resulting from altered K+ channel function. Thu...Keywords
This publication has 27 references indexed in Scilit:
- Superoxide-NO interaction decreases flow- and agonist-induced dilations of coronary arterioles in Type 2 diabetes mellitusAmerican Journal of Physiology-Heart and Circulatory Physiology, 2003
- Association Between Diabetes and Stroke Subtype on Survival and Functional Outcome 3 Months After StrokeStroke, 2003
- Mechanisms of Increased Vascular Superoxide Production in Human Diabetes MellitusCell Metabolism, 2002
- Global and societal implications of the diabetes epidemicNature, 2001
- Relationship between Inward Rectifier Potassium Current Impairment and Brain Injury after Cerebral Ischemia/ReperfusionJournal of Cerebral Blood Flow & Metabolism, 1999
- Impaired Endothelium-Mediated Relaxation in Coronary Arteries from Insulin-Resistant Rats1Journal of Vascular Research, 1999
- Kir2.1 encodes the inward rectifier potassium channel in rat arterial smooth muscle cellsThe Journal of Physiology, 1999
- Role of Potassium Channels in Regulation of Cerebral Vascular ToneJournal of Cerebral Blood Flow & Metabolism, 1998
- Hyperinsulinemia Is Associated With the Incidence of Hypertension and Dyslipidemia in Middle-Aged MenDiabetes, 1998
- Arterial dilations in response to calcitonin gene-related peptide involve activation of K+ channelsNature, 1990