Videodermoscopy compared to reflectance confocal microscopy for the diagnosis of scabies
- 11 May 2016
- journal article
- research article
- Published by Wiley in Journal of the European Academy of Dermatology and Venereology
- Vol. 30 (9), 1573-1577
- https://doi.org/10.1111/jdv.13676
Abstract
Reflectance confocal microscopy (RCM) and dermoscopy have recently been suggested for non-invasive diagnosis of scabies. However, there are large studies on diagnostic accuracy for scabies only with dermoscopy at low (10×) and high (100-1000×) magnification.Our study evaluated the diagnostic accuracy, for the diagnosis of scabies, of RCM and videodermoscopy at intermediate (20× and 70×) magnification, which is usually found in commercially available videodermoscopes.Patients with a presumptive diagnosis of scabies were prospectively enrolled during 20 months and examined by RCM and videodermoscopy at intermediate magnification. The specificity of RCM was considered 100% because RCM can identify the anatomical details of the parasites.A total of 148 patients were enrolled. Videodermoscopy showed a higher sensitivity for scabies than RCM (95% vs. 92%) and a specificity of 97%.Videodermoscopy at intermediate magnification, and RCM are both highly accurate for the diagnosis of scabies. If the two devices are available, it would be better to perform videodermoscopy first, that is more sensitive, and then RCM to confirm the diagnosis.Keywords
This publication has 13 references indexed in Scilit:
- Diagnostic de la gale par épimicroscopie à fort grossissement : l’aspect « en deltaplane » de Sarcoptes scabieiAnnales de Dermatologie et de Vénéréologie, 2013
- Microscopie confocale pour le diagnostic de la gale : questions sur la faisabilitéAnnales de Dermatologie et de Vénéréologie, 2013
- Reflectance confocal microscopy for quantification ofSarcoptes scabieiin Norwegian scabiesJournal of the European Academy of Dermatology and Venereology, 2012
- Comparison of Dermoscopy, Skin Scraping, and the Adhesive Tape Test for the Diagnosis of Scabies in a Resource-Poor SettingArchives of Dermatology, 2011
- Detection of Scabies: A Systematic Review of Diagnostic MethodsCanadian Journal of Infectious Diseases and Medical Microbiology, 2011
- Accuracy of standard dermoscopy for diagnosing scabiesJournal of the American Academy of Dermatology, 2006
- Videodermatoscopy enhances the ability to monitor efficacy of scabies treatment and allows optimal timing of drug applicationJournal of the European Academy of Dermatology and Venereology, 2004
- Scabies and Pediculosis Pubis: An Update of Treatment Regimens and General ReviewClinical Infectious Diseases, 2002
- Nodular Scabies Detected by Computed DermatoscopyDermatology, 2001
- Epiluminescence MicroscopyArchives of Dermatology, 1997