Factors contributing to the inhibition of HIV reverse transcriptase by chain‐terminating nucleotides in vitro and in vivo
Open Access
- 7 October 1991
- journal article
- review article
- Published by Wiley in FEBS Letters
- Vol. 291 (1), 1-5
- https://doi.org/10.1016/0014-5793(91)81089-q
Abstract
Arguments are presented leading to the conclusion that two major factors contribute to the potency of inhibition of DNA‐polymerase activity by chain‐terminating nucleotides. The relative significance...Keywords
This publication has 3 references indexed in Scilit:
- Molecular Targets for AIDS TherapyScience, 1990
- Herpes simplex virus type 1 DNA polymeraseJournal of Biological Chemistry, 1989
- Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase.Proceedings of the National Academy of Sciences, 1986