βγ-Dehydrocurvularin and Related Compounds as Nematicides ofPratylenchus penetransfrom the FungusAspergillussp.

Abstract

The new nematicidal compound, βγ-dehydrocurvularin (1), together with three known compounds, αβ-dehydrocurvularin (2), 8-β-hydroxy-7-oxocurvularin (3) and 7-oxocurvularin (4), were isolated from the culture filtrate and mycelial mats of Aspergillus sp. The structures of 1-4 were established by spectroscopic methods including 2D NMR. The biological activities of 1-4 were examined by bioassays with root-lesion nematodes, and lettuce and rice seedlings.