Understanding the Behavior of Systems Pharmacology Models Using Mathematical Analysis of Differential Equations: Prolactin Modeling as a Case Study
Open Access
- 12 July 2016
- journal article
- tutorial
- Published by Wiley in CPT: Pharmacometrics & Systems Pharmacology
- Vol. 5 (7), 339-351
- https://doi.org/10.1002/psp4.12098
Abstract
No abstract availableKeywords
This publication has 25 references indexed in Scilit:
- Towards a European Strategy for Medicines Research (2014–2020): The EUFEPS Position Paper on Horizon 2020European Journal of Pharmaceutical Sciences, 2012
- Pharmacokinetic-Pharmacodynamic Modeling of the D2 and 5-HT2A Receptor Occupancy of Risperidone and Paliperidone in RatsPharmaceutical Research, 2012
- Coping with time scales in disease systems analysis: application to bone remodelingJournal of Pharmacokinetics and Pharmacodynamics, 2011
- Impact of plasma-protein binding on receptor occupancy: An analytical descriptionJournal of Theoretical Biology, 2009
- What Can We Learn from Rodents about Prolactin in Humans?Endocrine Reviews, 2007
- Cell Surface Receptors for Signal Transduction and Ligand Transport: A Design Principles StudyPLoS Computational Biology, 2007
- Prolactin in man: a tale of two promotersBioEssays, 2006
- Robustness and modular design of the Drosophila segment polarity networkMolecular Systems Biology, 2006
- Precursor-dependent indirect pharmacodynamic response model for tolerance and rebound phenomena††Supported in part by Grant No. 24211 from the National Institute of General Medical Science, National Institutes of Health.Journal of Pharmaceutical Sciences, 1998
- Influence of the dosing interval on prolactin release after remoxipride.British Journal of Clinical Pharmacology, 1995