SESAME OIL AS A VEHICLE FOR FAT SOLUBLE HORMONES1

Abstract

Sesame oil may prevent the expected effect of small amts. of a hormone dissolved in it. Injns. of small doses of androsterone dissolved in sesame oil into immature [male] mice for 10 days were followed by a reduction in wt. of the prostate and seminal vesicles. Subcut. injns. of sesame oil alone produced a similar decrease in the wt. of the prostate and seminal vesicles of immature [male] mice. Sesame oil did not produce a significant change in the wt. of the prostate and seminal vesicles of adult mice treated for 30 days with 0.2 and 0.3 cc. per day.