Isolation and Identification of the Principal Fungitoxic Component of Turmeric Essential Oil
- 1 July 2007
- journal article
- research article
- Published by Informa UK Limited in Journal of Essential Oil Research
- Vol. 19 (4), 387-391
- https://doi.org/10.1080/10412905.2007.9699312
Abstract
The essential oil of turmeric (Curcuma longa L.) rhizomes showed toxicity to seven fungi involved in deterioration of stored agricultural commodities. Depending upon the fungus, in vitro growth inhibition varied from 36%-77% at 0.1%. Aspergillus flavus, Fusarium semitectum, Colletotrichum gloeosporioides and C. musae were most sensitive with growth inhibition of over 70%. The bioautography of the oil produced only one antifungal band representing 40% of the total oil. The fractionation of this band by reverse phase preparative HPLC (high performance liquid chromatography) yielded two peaks, in the proportion of 57.9% and 42.1%. The larger peak had only one compound, which was identified as ar-turmerone by MS (mass spectrometry) and NMR (nuclear magnetic resonance) spectra. The smaller peak contained two compounds, in the proportion of 31% and 69%, which were identified as β-turmer-one and ar-turmerone, respectively. Thus ar-turmerone constituted 87% of the fungitoxic component of the oil. The purified ar-turmerone showed antifungal activity similar to the crude oil.Keywords
This publication has 12 references indexed in Scilit:
- Antimicrobial Activity and Cytotoxicity of the Essential Oil of Curcuma zedoariaThe American Journal of Chinese Medicine, 2004
- Antifungal Activity of Some Essential OilsJournal of Agricultural and Food Chemistry, 2003
- Fungicidal Property of Curcuma longa L. Rhizome-Derived Curcumin against Phytopathogenic Fungi in a GreenhouseJournal of Agricultural and Food Chemistry, 2003
- Chemical Composition of Essential Oils from Rhizomes, Leaves and Flowers of Curcuma longa L. from Reunion IslandJournal of Essential Oil Research, 2002
- Essential oil composition of Curcuma longa L. cv. Roma from the plains of northern IndiaFlavour and Fragrance Journal, 2002
- The curcuma antioxidants: pharmacological effects and prospects for future clinical use. A reviewArchives of Gerontology and Geriatrics, 2001
- Chemical Composition of Turmeric Oil -A Byproduct from Turmeric Oleoresin Industry and Its Inhibitory Activity against Different FungiZeitschrift für Naturforschung C, 2001
- Antibacterial Activity of Turmeric Oil: A Byproduct from Curcumin ManufactureJournal of Agricultural and Food Chemistry, 1999
- Antifungal Activity of Selected Essential Oils, Cinnamaldehyde and Carvacrol againstMalassezia furfurandCandida albicansJournal of Essential Oil Research, 1999
- Essential Oils ofCurcuma longaL. from BhutanJournal of Essential Oil Research, 1997