Effects of chlorhexidine, NaF and SnF2 on glucan formation by salivary and culture supernatant GTF adsorbed to hydroxyapatite

Abstract

– Chlorhexidine, NaF and SnF₂ were tested for inhibitory activity against glucosyltrans-ferase (GTF) which had been adsorbed to hydroxyapatite. The sources of GTF were culture supernatants of S. mutans grown in BHI or stimulated whole saliva supernatants. Chlorhexidine inhibited GTF activity from culture supernatants as well as from saliva. NaF and SnF₂ had moderate effects.