Simplified Microneutralization Test for Serotyping Adenovirus Isolates
Open Access
- 1 August 2001
- journal article
- research article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 39 (8), 2984-2986
- https://doi.org/10.1128/jcm.39.8.2984-2986.2001
Abstract
A simplified microneutralization procedure is described that uses an empirically determined virus challenge dose, a single dilution of antiserum, and observation of cytopathic effect to determine the adenovirus serotype. The simplified test has faster turnaround time and was 96% concordant with a confirmatory test using serial dilutions of type-specific sera. This method will find utility in high-volume serotyping work.Keywords
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