Somatostatin release and plasma molecular somatostatin components in man

Abstract
A sensitive, precise and specific radioimmunoassay method for measurements of plasma somatostatin is described, as well as a significant rises in plasma somatostatin following a test meal, intraduodenal infusion of fat and HCl and i.v. injection of insulin. Separation of immunoreactive plasma somatostatin into 2 components probably representing bound and free molecular forms of somatostatin both in fasting and postprandial human plasmas were found.