The Integral Role of Clinical Research in Clinical Care
- 3 April 2003
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 348 (14), 1386-1388
- https://doi.org/10.1056/nejmsb025342
Abstract
The ethical justification for clinical research as currently conducted has been questioned on the grounds that physicians do not make a strict and unequivocal distinction for their patients between clinical research and clinical care, and their patients may therefore participate in clinical studies with the false impression that they are being cared for to the best of their physicians' ability.1 This issue raises difficult and controversial questions about the intentions, goals, and responsibilities of clinical researchers, as evidenced by the numerous editorials and articles on the subject that have appeared in the Journal in recent decades.26 These are certainly . . .Keywords
This publication has 18 references indexed in Scilit:
- The Therapeutic Orientation to Clinical TrialsNew England Journal of Medicine, 2003
- Discrepancy between Consensus Recommendations and Actual Community Use of Adjuvant Chemotherapy in Women with Breast CancerAnnals of Internal Medicine, 2003
- Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled TrialJAMA, 2002
- Protecting Research Subjects — The Crisis at Johns HopkinsNew England Journal of Medicine, 2002
- Overview of the six available randomized trials of high-dose chemotherapy with blood or marrow transplant in breast cancer.JNCI Monographs, 2001
- The Ethics of Placebo-Controlled Trials — A Middle GroundNew England Journal of Medicine, 2001
- How to Resolve an Ethical Dilemma Concerning Randomized Clinical TrialsNew England Journal of Medicine, 1999
- Clinical Trials — Are They Ethical?New England Journal of Medicine, 1991
- Equipoise and the Ethics of Clinical ResearchNew England Journal of Medicine, 1987
- The Ethics of the Randomized Clinical TrialNew England Journal of Medicine, 1982