Pseudohyperkalemia with Thrombocytosis

Abstract

ELEVATED serum potassium levels usually result from deranged metabolic processes in renal or adrenal dysfunction whose detection often involves extensive laboratory investigation. Clinical and electrocardiographic findings are corroborative in these cases. Increased serum potassium values without such corollaries occur with the thrombocytosis of some myeloproliferative diseases.^{1 2 3 4 5} Appreciation of the extent to which potassium is released under certain conditions during thrombocyte degradation may prevent needless adrenal and renal evaluation.This report illustrates the relation between pseudohyperkalemia and thrombocytosis associated with myeloproliferative disease. Some laboratory studies on the mechanisms involved, serial observations of the changes during therapy and a review of the . . .