Abstract
Reduced pyridine nucleotides are oxidatively catalyzed in weakly acidic solutions. The rate is proportional to the acidity, and at constant acidic pH, the reaction follows first-order kinetics. The rate of oxidation of reduced triphosphopyridine nucleotide is approximately 3 times that of reduced diphosphopyridine nucleotide. The reaction offers a very plausible explanation for the metabolic efficiency of the malignant tumor cell. It may also play a key role in wound healing and muscle contraction.

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