Treatment of Plasmodium falciparum malaria with a combination of amodiaquine and tetracycline in Central Thailand
- 31 December 1983
- journal article
- Published by Oxford University Press (OUP) in Transactions of the Royal Society of Tropical Medicine and Hygiene
- Vol. 77 (3), 338-340
- https://doi.org/10.1016/0035-9203(83)90158-x
Abstract
A combination of the drugs amodiaquine and tetracycline was used in a clinical trial at Phrabuddhabat Hospital in Central Thailand for treating Plasmodium falciparum malaria. Of the 51 patients who completed the 28-day follow-up, 49 (96%) were cured; in two cases the parasitaemia was cleared within seven days of initial therapy but returned within 28 days (RI response). Only one patient experienced a mild and transient side effect of nausea. The treatment regimen was cheap and the drugs are readily available commercially. Results of this study suggest that amodiaquine-tetracycline combination offers a practical, safe and highly effective method for treating uncomplicated falciparum malaria.Keywords
This publication has 4 references indexed in Scilit:
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