Chromatographic studies on nucleic acids. 3. The nucleic acids of five strains of tobacco mosaic virus

Abstract

The nucleic acids from 5 strains of tobacco mosaic virus (tobacco mosaic, tomato mosaic 844A, tomato aucuba mosaic, rib-grass virus, cucumber virus 4) were isolated and their composition studied by means of paper chromatography. The purine-bound sugar from the nucleic acids of tobacco mosaic and tomato mosaic strains has been shown by paper chromatography to be identical with ribose from yeast nucleic acid. All the nucleic acids were shown by chromatographic technic to contain only the 4 bases, adenine, guanine, cytosine and uracil. The nucleotide compositions of the nucleic acids from the 5 strains were very similar. Small significant differences were detected among 3 of the strains.