Extensively heated milk and egg as oral immunotherapy
- 1 June 2012
- journal article
- review article
- Published by Ovid Technologies (Wolters Kluwer Health) in Current Opinion in Allergy and Clinical Immunology
- Vol. 12 (3), 283-292
- https://doi.org/10.1097/aci.0b013e3283535bc3
Abstract
The introduction of extensively heated milk and egg protein into the diet has been explored in recent years. Studies have suggested that a large subset of children who react to unheated milk or egg can tolerate extensively heated forms of these foods. Immunologic changes induced by a diet containing baked milk and egg are similar to changes that have been observed during oral immunotherapy trials. The baked milk and egg diet appears to accelerate the development of regular milk and egg tolerance when compared with strict avoidance. An oral challenge to extensively heated milk and egg into milk and egg allergic children's diets should be considered when appropriate. Oral food challenges are the most reliable means of establishing a diagnosis and should be undertaken under physician supervision.Keywords
This publication has 40 references indexed in Scilit:
- Dietary baked milk accelerates the resolution of cow’s milk allergy in childrenJournal of Allergy and Clinical Immunology, 2011
- Oral immunotherapy for food allergyCurrent Opinion in Pediatrics, 2010
- Correlation of IgE/IgG4 milk epitopes and affinity of milk-specific IgE antibodies with different phenotypes of clinical milk allergyJournal of Allergy and Clinical Immunology, 2010
- Allergen-specific basophil suppression associated with clinical tolerance in patients with milk allergyJournal of Allergy and Clinical Immunology, 2009
- Association of allergen-specific regulatory T cells with the onset of clinical tolerance to milk proteinJournal of Allergy and Clinical Immunology, 2009
- Immunologic changes in children with egg allergy ingesting extensively heated eggJournal of Allergy and Clinical Immunology, 2008
- Tolerance to cooked egg in an egg allergic populationAllergy, 2006
- IgE and IgG Binding Epitopes on α-Lactalbumin and β-Lactoglobulin in Cow’s Milk AllergyInternational Archives of Allergy and Immunology, 2001
- Anaphylactic reactions to raw eggs after negative challenges with cooked eggsJournal of Allergy and Clinical Immunology, 2000
- Allergenic activity of heated and ovomucoid-depleted egg whiteJournal of Allergy and Clinical Immunology, 1997