Unrepaired DNA Breaks in p53-Deficient Cells Lead to Oncogenic Gene Amplification Subsequent to Translocations
- 1 June 2002
- journal article
- research article
- Published by Elsevier BV in Cell
- Vol. 109 (7), 811-821
- https://doi.org/10.1016/s0092-8674(02)00770-5
Abstract
No abstract availableKeywords
This publication has 58 references indexed in Scilit:
- Multiple myeloma: evolving genetic events and host interactionsNature Reviews Cancer, 2002
- Different types of V(D)J recombination and end-joining defects in DNA double-strand break repair mutant mammalian cellsEuropean Journal of Immunology, 2002
- Clinical Resistance to STI-571 Cancer Therapy Caused by BCR-ABL Gene Mutation or AmplificationScience, 2001
- Jumping translocations are common in solid tumor cell lines and result in recurrent fusions of whole chromosome armsGenes, Chromosomes and Cancer, 2001
- DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformationNature, 2000
- Oncogene amplification in solid tumorsSeminars in Cancer Biology, 1999
- Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 allelesCell, 1992
- Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53Cell, 1992
- p53, guardian of the genomeNature, 1992
- Distinctive chromosomal structures are formed very early in the amplification of CAD genes in Syrian hamster cellsCell, 1990