Humanised IgG1 antibody variants targeting membrane-bound carcinoembryonic antigen by antibody-dependent cellular cytotoxicity and phagocytosis
Open Access
- 10 November 2009
- journal article
- Published by Springer Science and Business Media LLC in British Journal of Cancer
- Vol. 101 (10), 1758-1768
- https://doi.org/10.1038/sj.bjc.6605355
Abstract
Background: Methods: Results: Conclusion:Keywords
This publication has 54 references indexed in Scilit:
- In vitro and in vivo anticancer efficacy of unconjugated humanised anti-CEA monoclonal antibodiesBritish Journal of Cancer, 2008
- Detection of circulating tumour cells in peripheral blood with an automated scanning fluorescence microscopeBritish Journal of Cancer, 2008
- Immunoglobulin G Fragment C Receptor Polymorphisms and Clinical Efficacy of Trastuzumab-Based Therapy in Patients With HER-2/neu–Positive Metastatic Breast CancerJournal of Clinical Oncology, 2008
- Targeted killing of colorectal cancer cell lines by a humanised IgG1 monoclonal antibody that binds to membrane-bound carcinoembryonic antigenBritish Journal of Cancer, 2008
- Plasmacytoid dendritic cells of melanoma patients present exogenous proteins to CD4+ T cells after FcγRII-mediated uptakeThe Journal of Experimental Medicine, 2006
- Empowering Targeted Therapy: Lessons from RituximabScience's STKE, 2004
- Directed evolution of an anti-carcinoembryonic antigen scFv with a 4-day monovalent dissociation half-time at 37 CProtein Engineering, Design and Selection, 2004
- Inducing Tumor Immunity through the Selective Engagement of Activating Fcγ Receptors on Dendritic CellsThe Journal of Experimental Medicine, 2002
- Transplantation of mobilized peripheral blood cells to HLA-identical siblings with standard-risk leukemiaBlood, 2002
- Replacing the complementarity-determining regions in a human antibody with those from a mouseNature, 1986