The presence of IgA on the surface of rat thoractic duct lymphocytes which contain internal IgA.
Open Access
- 1 February 1975
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 141 (2), 335-345
- https://doi.org/10.1084/jem.141.2.335
Abstract
The presence of lymphocytes with internal IgA among cells from rat thoracic duct lymph wdy. The number of cells detected was greater in animals kept in a convential animal house compared with those maintained under specific pathogen-free conditions. Thoracic duct lymph from B rats and adult thymectomized rats also contained cell with internal IgA. The surface Ig of the IgA-containing cells was studied using a double-labeling technique with (126I) anti-Ig to detect surface Ig, and fluorescein-conjugated anti-IgA in large amounts, but very little IgM and no surface IgG2. The surface IgA was not acquired passively.Keywords
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