Effect of different antioxidants and free radical scavengers on aflatoxin production
- 1 September 1985
- journal article
- Published by Springer Science and Business Media LLC in Mycotoxin Research
- Vol. 1 (2), 65-69
- https://doi.org/10.1007/bf03192005
Abstract
Different antioxidants and free radical scavengers on aflatoxin production are analysed. The different compounds at different concentration were used: buthylated hydroxyanisole (BHA), buthylated hydroxytoluene (BHT), α-tocopherol (vitamin E), ascorbic acid (vitamin C), reduced glutathione, cysteine, cysteamine. The above compounds were tested in culture ofAspergillus parasiticus supplemented with carbon tetrachloride, a potent stimulating agent of aflatoxin biosynthesis. Cysteamine and BHA highly inhibited the aflatoxin production induced by carbon tetrachloride, the inhibition decreased by lowering the concentration. On the contrary, vitamin E, vitamin C, reduced glutathione and cysteine further enhanced the carbon tetrachloride stimulating effect. The addition of the above compounds did not significantly affect the growth of the fungal mycelia.Keywords
This publication has 9 references indexed in Scilit:
- Free radicals and aflatoxin biosynthesisCellular and Molecular Life Sciences, 1984
- Cerulenin and tetrahydrocerulenin: Stimulating factors of aflatoxin biosynthesisTransactions of the British Mycological Society, 1983
- Stimulation of Aflatoxin Biosynthesis by Lipophilic EpoxidesMicrobiology, 1983
- Growth requirements and lipid metabolism of Aspergillus FlavusTransactions of the British Mycological Society, 1980
- Vitamin E and Lipid Antioxidants in Free-Radical-Initiated ReactionsPublished by Elsevier BV ,1980
- Free-Radical Damage in LiverPublished by Elsevier BV ,1980
- Chemical Mechanisms in Carbon Tetrachloride ToxicityPublished by Elsevier BV ,1977
- Application of Radiation Chemistry to BiologyPublished by Elsevier BV ,1977
- The Glutathione–Glutathione Disulfide SystemPublished by Elsevier BV ,1976