Basosquamous Carcinoma: Controversy, Advances, and Future Directions
- 1 January 2017
- journal article
- review article
- Published by Ovid Technologies (Wolters Kluwer Health) in Dermatologic Surgery
- Vol. 43 (1), 23-31
- https://doi.org/10.1097/dss.0000000000000815
Abstract
Basosquamous carcinoma is a rare cutaneous neoplasm that has caused considerable controversy as to its classification, pathogenesis, and management. To review and summarize current literature on the definition, pathogenesis, incidence, and management of basosquamous carcinoma. Through December 2015, an electronic search of the Pubmed database was performed using combinations of basosquamous carcinoma and metatypical basal cell carcinoma as search terms. A selection of 39 publications including case reports and series, retrospective studies, and systematic reviews of the literature were included. Descriptions of the definition of basosquamous carcinoma, clinical behavior, histopathological characteristics, current treatment therapies, and future advances are summarized. This systematic review provides a comprehensive overview of the current understanding of basosquamous carcinoma. Further study is required to elucidate the mechanisms driving the formation of this aggressive tumor.Keywords
This publication has 42 references indexed in Scilit:
- Basosquamous carcinoma and metatypical basal cell carcinoma: a review of treatment with Mohs micrographic surgeryInternational Journal of Dermatology, 2014
- Basosquamous cell carcinoma: a survey of 76 patients and a comparative analysis of basal cell carcinomas and squamous cell carcinomasEuropean Journal Of Dermatology, 2013
- Features of biopsy in diagnosis of metatypical basal cell carcinoma (Basosquamous Carcinoma) of head and neckPolski Przegląd Otorynolaryngologiczny, 2012
- Basosquamous carcinomaJournal of the American Academy of Dermatology, 2009
- Metatypical basal cell carcinoma: a clinical reviewJournal of Experimental & Clinical Cancer Research, 2008
- Ber EP4 and epithelial membrane antigen aid distinction of basal cell, squamous cell and basosquamous carcinomas of the skinHistopathology, 2000
- Basosquamous carcinomaCancer, 2000
- The Immunohistochemical Characteristics of the Basosquamous Cell CarcinomaDermatologic Surgery, 1997
- Basal cell carcinoma of the skin with areas of squamous cell carcinoma: a basosquamous cell carcinoma?Journal of Clinical Pathology, 1985
- THE PROBLEMS OF HISTOLOGICAL DIAGNOSIS IN BASO-SQUAMOUS CELL CARCINOMA OF THE SKINJournal of Clinical Pathology, 1959