Frequency and spectrum of congenital heart defects among live births in Germany
- 10 September 2011
- journal article
- research article
- Published by Springer Science and Business Media LLC in Clinical Research in Cardiology
- Vol. 100 (12), 1111-1117
- https://doi.org/10.1007/s00392-011-0355-7
Abstract
Background Congenital heart defects (CHD) are the most common single organ malformations in humans. A comprehensive study was initiated within the Competence Network for Congenital Heart Defects to assess population-based nationwide prevalence data for Germany. Methods Study register of demographic and medical data of live births with CHD born between July 2006 and June 2007. Results Seven thousand two hundred forty-five live births and infants with CHD were registered in Germany by 260 participating institutions (prevalence 107.6 per 10,000 live births). The most common lesions were ventricular septal defect, atrial septal defect and valvular pulmonary stenosis with 52.7, 18.3 and 6.6 per 10,000 live births, respectively. A single ventricle, tetralogy of Fallot and the complete transposition of the great arteries were the most common severe cardiac lesions (3.0, 2.7 and 2.3 per 10,000 live births). Parents reported that prenatal echocardiography had been performed in 53.8% of severe CHD cases with a cardiac defect detected in 77.5% of them. Conclusion The reported prevalences of severe CHD are within the range of regional and European comparative data. The prenatal detection rate of severe cardiovascular malformations is comparable to contemporary European registries. Postnatal diagnosis of the CHD has been made early in life.Keywords
This publication has 18 references indexed in Scilit:
- Prevalence of Congenital Heart Defects in Newborns in Germany: Results of the First Registration Year of the PAN Study (July 2006 to June 2007)Klinische Padiatrie, 2010
- A Data Protection Scheme for Medical Research NetworksMethods of Information in Medicine, 2010
- Spectrum of congenital heart defects in CroatiaEuropean Journal of Pediatrics, 2009
- Congenital heart disease in 111 225 births in Belgium: birth prevalence, treatment and survival in the 21st centuryActa Paediatrica, 2009
- Report of the Coding Committee of the Association for European Paediatric CardiologyCardiology in the Young, 2002
- Prevalence and secular trend of congenital anomalies in Glasgow, UKArchives of Disease in Childhood, 2002
- Evaluation of prenatal diagnosis of congenital heart diseases by ultrasound: experience from 20 European registriesUltrasound in Obstetrics & Gynecology, 2001
- Monitoringsystem angeborener FehlbildungenPerinatalMedizin, 1998
- Registries of congenital anomalies: EUROCAT.Environmental Health Perspectives, 1993
- Congenital Heart Disease in 56,109 Births Incidence and Natural HistoryCell Metabolism, 1971