Expression of tissue polypeptide antigen (TPA) in fetal and adult liver: changes in liver disease.
Open Access
- 1 July 1987
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 40 (7), 719-724
- https://doi.org/10.1136/jcp.40.7.719
Abstract
The distribution of tissue polypeptide antigen (40 kD molecular weight) in normal adult and fetal liver, and in liver disease was investigated and compared with the distribution of low and high molecular weight cytokeratins. In normal liver tissue polypeptide antigen was found only in bile duct epithelium; this distribution is similar to that of high molecular weight cytokeratin, but differs from that of low molecular weight cytokeratins. In liver disease it was found in areas of ductular transformation; in Mallory's bodies; and in alcoholic liver disease and primary biliary cirrhosis in some hepatocytes that did not contain Mallory's bodies.This publication has 31 references indexed in Scilit:
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