IS 26 -Associated In4-Type Integrons Forming Multiresistance Loci in Enterobacterial Plasmids
Open Access
- 1 August 2005
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 49 (8), 3541-3543
- https://doi.org/10.1128/aac.49.8.3541-3543.2005
Abstract
Three distinct multiresistant loci from enterobacterial plasmids each comprised an integron and an IS 26 -associated sequence. Sequence comparison suggested a common ancestral structure that derived from an IS 26 insertion into the 5′ conserved segment of an In4-type integron and evolved through acquisition of gene cassettes and IS 26 -mediated recruitment of additional resistance genes of diverse origin.Keywords
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