Editorial

Abstract

This is a short review and discussion of the physiologic functions of the lymphatic system with particular emphasis on its role in homeostasis. These are discussed with respect to its role in prevention of excessive change in the composition of interstitial fluid; assistance in the maintenance of constant plasma levels of proteins, lipids and fluid; transport of enzymes, fats and other substances from their sites of origin in cells to the blood stream. A tentative concept is suggested to explain the one-way permeability of lymphatics. It is suggested that lymphatic capillaries are freely permeable but the permeability decreases as the vessels get larger where only substances with a molecular weight of less than 2000 leave the lymphatic system in any significant amount.