The pattern of projection of cortical areas 17, 18, and 19 onto the laminae of the dorsal lateral geniculate nucleus in the cat
- 9 October 1975
- journal article
- research article
- Published by Wiley in Journal of Comparative Neurology
- Vol. 163 (4), 377-395
- https://doi.org/10.1002/cne.901630402
Abstract
The projection of cortical areas 17, 18, and 19 onto the laminar part of the dorsal lateral geniculate nucleus was investigated with degeneration methods and with the autoradiographic axon tracing method. In agreement with previous accounts, degenerating cortical axons stained by the Nauta method were restricted to laminae A, A1, C and to the interlaminar zones. In contrast, adjacent sections stained with the Fink-Heimer method showed fine dust like degeneration throughout all of the laminae of the nucleus. Comparisons of Fink-Heimer degeneration resulting from lesions of area 17 with that resulting from lesions of areas 18 and 19 further suggested that the area 17 projection is heavier and more uniform than the projections from areas 18 and 19. Autoradiographic tracing of axons after intracortical injections of 3H-proline provided detailed demonstrations of the cortical projection patterns that confirmed the Fink-Heimer results. Following restricted injections of areas 17 or 18 the termination zones in the dorsal lateral geniculate nucleus consisted of columns of labeled tissue oriented perpendicular to the laminae of the nucleus. Area 17 was found to project heavily and uniformly throughout all of the laminae of the nucleus. The projection from area 18 also extended throughout all of the laminae of the nucleus, but was sparser and less uniformly distributed than that from area 17. Projections from area 18 distributed more heavily to the interlaminar zones and to lamina C than to laminae A, A1, C1, C2, or C3. A projection from area 19 to laminae C1, C2, and C3 was also demonstrated autoradiographically.Keywords
This publication has 42 references indexed in Scilit:
- Striate cortex projections to the lateral geniculate and other thalamic nuclei; a study using degeneration and autoradiographic tracing methods in the marmosetCallithrixBrain Research, 1974
- The projection of the visual field to the lateral geniculate and medial interlaminar nuclei in the catJournal of Comparative Neurology, 1971
- Interrelationships of striate and extrastriate cortex with the primary relay sites of the visual pathway.Journal of Neurology, Neurosurgery & Psychiatry, 1968
- Centrifugal fibers to the retina and olfactory bulb, and composition of the supraoptic commissures in the rabbitExperimental Neurology, 1962
- Effects of corticipetal and corticifugal impulses upon single elements of the dorsolateral geniculate nucleusExperimental Neurology, 1960
- Efferent connections of the striate cortex in the albino ratJournal of Comparative Neurology, 1954
- Silver Impregnation of Degenerating Axons in the Central Nervous System: A Modified TechnicStain Technology, 1954
- Corticifugal fiber connections of the cortex of Macaca mullatta. The occipital regionJournal of Comparative Neurology, 1935
- Studies on the diencephalon of the cat. I. The cyto‐architecture of the corpus geniculatum lateraleJournal of Comparative Neurology, 1928
- Ueber den Verlauf der centralen Sehfasern (Rinden-Sehhügelfasern) und deren Endigung im Zwischen- und Mittelhirne und über die Associations- und Commissurenfasern der SehsphäreArchiv Fur Psychiatrie Und Nervenkrankheiten, 1901