The Concise Guide to PHARMACOLOGY 2013/14: Overview
Open Access
- 17 December 2013
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 170 (8), 1449-1458
- https://doi.org/10.1111/bph.12444
Abstract
The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties from the IUPHAR database. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.12444/full. This compilation of the major pharmacological targets is divided into seven areas of focus: G protein-coupled receptors, ligand-gated ion channels, ion channels, catalytic receptors, nuclear hormone receptors, transporters and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets. It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in previous Guides to Receptors & Channels. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.Keywords
This publication has 43 references indexed in Scilit:
- Adiponectin receptor signalling in the brainBritish Journal of Pharmacology, 2011
- Guide to Receptors and Channels (GRAC), 5th editionBritish Journal of Pharmacology, 2011
- Tissue-specific Functions in the Fatty Acid-binding Protein FamilyJournal of Biological Chemistry, 2010
- Structural and Functional Characterization of Human Peripheral Nervous System Myelin Protein P2PLOS ONE, 2010
- Identification and Characterization of a Small Molecule Inhibitor of Fatty Acid Binding ProteinsJournal of Medicinal Chemistry, 2009
- Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategiesTrends in Pharmacological Sciences, 2009
- Protective vascular and myocardial effects of adiponectinNature Clinical Practice Cardiovascular Medicine, 2008
- Fatty acid-binding proteins: role in metabolic diseases and potential as drug targetsNature Reviews Drug Discovery, 2008
- Cloning of adiponectin receptors that mediate antidiabetic metabolic effectsNature, 2003
- cDNA Cloning and Expression of a Novel Adipose Specific Collagen-like Factor, apM1 (AdiposeMost Abundant Gene Transcript 1)Biochemical and Biophysical Research Communications, 1996