Some theoretical derivations relating to the tissue dosimetry of brachytherapy nuclides, with particular reference to iodine-125

Abstract

Using a Monte Carlo computer technique, tables of parameters were derived which were of use in the dosimetry of brachytherapy nuclides in a variety of tissues and organs. It was possible to derive relationships linking the composition of a tissue with the dose received at any location around an implanted source. Other factors, such as the relative importance of scattered radiation, spectral degradation, and integral dose, were discussed. In particular, attention was drawn to possible dosimetric problems arising from the clinical use of 125I.