Intermittent micromotion inhibits bone ingrowth
Open Access
- 1 January 1992
- journal article
- research article
- Published by Medical Journals Sweden AB in Acta Orthopaedica
- Vol. 63 (2), 141-145
- https://doi.org/10.3109/17453679209154809
Abstract
We studied the effects of micromotion on bone ingrowth into a 1-mm canal through a titanium chamber implanted in the proximal tibia of rabbits. The implant surface became “osseointegrated,” but an interior core was movable, allowing the central portion of the canal to be moved in relation to the ends. Thus, the ingrowing bone in the canal had to pass an area of ad latus motion. When implanted in rabbit tibiae, the canal became filled with ingrown cancellous bone. Bone ingrowth was inhibited by 20 cycles of 0.5-mm movement applied during a 30-sec-ond period once daily. With this regimen, the canal was usually filled with vascularized fibrous tissue and significantly less bone. The micromotion chamber may enable detailed studies of the effects of different motion variables on ingrowth of bone.Keywords
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