A Simple Catalytic Method for the Regioselective Halogenation of Arenes
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- 19 May 2006
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 8 (12), 2523-2526
- https://doi.org/10.1021/ol060747f
Abstract
This paper describes a mild palladium-catalyzed method for the regioselective chlorination, bromination, and iodination of arene C-H bonds using N-halosuccinimides as oxidants. These transformations have been applied to a wide array of substrates and can provide products that are complementary to those obtained via conventional electrophilic aromatic substitution reactions. [reaction: see text]Keywords
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