RECURRENT APHTHOUS UVEITIS WITH MUCOCUTANEOUS LESIONS

Abstract

DURING the last few years a new syndrome has been described in the European literature of dermatology and ophthalmology,¹ a syndrome characterized by periodically recurring uveitis and a group of mucous and cutaneous symptoms, namely, cutaneous eruptions of various types and aphthae and ulcerations of the buccal and genital mucous membranes. This disease is not new, for the first observation seems to have been made by the French oculist Janin de Combe Blanche² in 1772. At the end of the nineteenth century and during the first three decades of the twentieth century a number of isolated observations were published under various titles : catamenial iridochoroiditis (Trousseau³) ; intermittent hypopyon, or periodic or recurrent hypopyon (Bitsch,⁴ Quaglino,⁵ Neuschüler⁶) ; septic iritis (Gilbert⁷) ; recurrent allergic uveitis (Weve⁸) ; aphthous uveitis (Dascalopoulos⁹), and, especially, recurring iritis with hypopyon. In a certain number of these observations the coexistence of