Randomized trial of modafinil as a treatment for the excessive daytime somnolence of narcolepsy
- 14 March 2000
- journal article
- clinical trial
- Published by Ovid Technologies (Wolters Kluwer Health) in Neurology
- Vol. 54 (5), 1166-1175
- https://doi.org/10.1212/wnl.54.5.1166
Abstract
Objective: This is one of two separate clinical trials to evaluate the efficacy and safety of modafinil, a novel wake-promoting agent, in patients with excessive daytime sleepiness (EDS) associated with narcolepsy.Keywords
This publication has 24 references indexed in Scilit:
- An evaluation of the abuse potential of modafinil using methylphenidate as a referenceJournal of Psychopharmacology, 2000
- Narcolepsy: A Key Role for Hypocretins (Orexins)Cell, 1999
- The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 GeneCell, 1999
- Narcolepsy in orexin Knockout MiceCell, 1999
- Randomized trial of modafinil for the treatment of pathological somnolence in narcolepsyAnnals of Neurology, 1998
- Potential brain neuronal targets for amphetamine-, methylphenidate-, and modafinil-induced wakefulness, evidenced by c- fos immunocytochemistry in the catProceedings of the National Academy of Sciences of the United States of America, 1996
- Non-amphetaminic mechanism of stimulant locomotor effect of modafinil in miceEuropean Neuropsychopharmacology, 1995
- Role of catecholamines in the modafinil and amphetamine induced wakefulness, a comparative pharmacological study in the catBrain Research, 1992
- NarcolepsyJournal Of Clinical Neurophysiology, 1990
- Sleep studies on canine narcolepsy: Pattern and cycle comparisons between affected and normal dogsElectroencephalography and Clinical Neurophysiology, 1977