THE EFFECT OF THE HEPTAPEPTIDE (2-8) AND HEXAPEPTIDE (3-8) FRAGMENTS OF ANGIOTENSIN II ON ALDOSTERONE SECRETION1

Abstract

The effect of local adrenal arterial infusion of the heptapeptide (2-8) and hexapeptide (3-8) fragments of angiotensin 11 on a aldosterone secretion was examined. The heptapeptide (2-8) resembled the octapeptide in activity and stimulated aldosterone whereas the hexapeptide (3-8) had no effect.