Frequency and Phenotype of Circulating Vα24/Vβ11 Double-Positive Natural Killer T Cells during Hepatitis C Virus Infection
Open Access
- 1 February 2003
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 77 (3), 2251-2257
- https://doi.org/10.1128/jvi.77.3.2251-2257.2003
Abstract
Natural killer T (NKT) cells are thought to be involved in innate responses against infection. We investigated one specific type of NKT cell, Vα24/Vβ11 double positive, in hepatitis C virus (HCV) infection. Lower frequencies of this population were detected in the blood of HCV PCR-positive patients than in controls. Unlike Vα24/Vβ11 NKT cells found in blood, those in the liver appeared to be recently activated.Keywords
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