MUSCULAR ATROPHY AND PSEUDOLOGIA FANTASTICA ASSOCIATED WITH ISLET CELL ADENOMA OF THE PANCREAS
- 1 September 1949
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology & Psychiatry
- Vol. 62 (3), 304-313
- https://doi.org/10.1001/archneurpsyc.1949.02310150051006
Abstract
A CASE is reported in which prolonged hypoglycemia due to an islet cell tumor of the pancreas was accompanied with an unusual array of symptoms due to widespread damage of the central nervous system. The patient had had repeated convulsions, periods of confusion and excitement, ataxia, muscular atrophy, intellectual impairment and pseudologia fantastica. After removal of the pancreatic adenoma, all abnormalities except the muscular atrophy disappeared. It has been recognized that deprivation of glucose essential for metabolism of the nerve cells can cause irreversible damage of the brain and spinal cord, but involvement of the central nervous system as extensive as in the present case has rarely been reported. Both the relationship of a syndrome resembling progressive muscular atrophy to spontaneous hypoglycemia and the recovery of a patient with pseudologia fantastica seem of unusual interest. REPORT OF A CASE The patient, a 23 year old veteran, came to our attentionKeywords
This publication has 2 references indexed in Scilit:
- NEUROHISTOPATHOLOGIC CHANGES WITH METRAZOL AND INSULIN SHOCK THERAPYArchives of Neurology & Psychiatry, 1940
- EXTRAPYRAMIDAL SYNDROME AND ENCEPHALOGRAPHIC PICTURE OF PROGRESSIVE INTERNAL HYDROCEPHALUS IN CHRONIC HYPOGLYCEMIAAnnals of Internal Medicine, 1936