Relation Between HLA‐B27 and Clinical Features in Patients with Yersinia Arthritis

Abstract

A study of 74 yersinia arthritis patients implied that the clinical picture of the disease may be modified by genetic background associated with the histocompatibility antigen B27 (HLA-B27). Sixty-six percent of patients were B27 positive. Joint symptoms were somewhat more severe in B27+ patients. Iritis, conjunctivitis, carditis, signs of urologic inflammation, and complete Reiter's triad occurred only in the B27+ group, whereas erythema nodosum was more common in B27— group. Several B27+ patients also had “B27+ rheumatic diseases,” such as ankylosing spondylitis or Reiter's disease, in their history.