Genetics of the Antibody Response to Dextran in Mice
- 14 July 1972
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 177 (4044), 178-180
- https://doi.org/10.1126/science.177.4044.178
Abstract
The immune response to dextran having the α-1,3 linkage may be under the control of antibody structural genes. Mice that respond well to this antigen produce antibody restricted with respect to light chain class (λ) and to an antigenic determinant resulting from a particular heavy and light chain interaction. The response to dextran is controlled by a locus linked to the-heavy chain locus.Keywords
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