Drug Induced Erythema Multiforme: Two Case Series with Review of Literature
Open Access
- 1 January 2014
- journal article
- review article
- Published by JCDR Research and Publications in Journal of Clinical and Diagnostic Research
- Vol. 8 (9), ZH01-4
- https://doi.org/10.7860/JCDR/2014/10173.4761
Abstract
Erythema Multiforme, (EM) an uncommon, acute inflammatory reactive mucocutaneous disorder and primary allergies confined to the oral mucosa. However the subsequent attacks can produce more severe forms of EM involving the skin. Manifestations of EM are varied and present a diagnostic dilemma because infections (particularly herpes simplex and mycoplasma pneumoniae) and drugs seem to predispose towards development of EM. We report two cases of EM in which drugs (Dioclofenac sodium & Amoxycilline) seems to be precipitating factor. In addition, the article reviews various aspects of EM as relevant to dental practice and highlight the associated potential etiologic agents, pathogenic mechanisms and therapies.Keywords
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