Laparoscopic Versus Open Partial Nephrectomy for the Treatment of Pathological T 1 N 0 M 0 Renal Cell Carcinoma: A 5-Year Survival Rate
- 1 November 2006
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Journal of Urology
- Vol. 176 (5), 1984-1989
- https://doi.org/10.1016/j.juro.2006.07.033
Abstract
We retrospectively compared the oncological adequacy of laparoscopic partial nephrectomy to that of open partial nephrectomy in the treatment of patients with pathological stage T1N0M0 renal cell carcinoma. A total of 143 patients with stage T1N0M0 renal tumors confirmed by pathological examination of the surgical specimen underwent partial nephrectomy between January 1996 and June 2004 with a followup of at least 1.5 years. Of these patients 85 were treated laparoscopically and the remaining 58 underwent open surgery. Medical and operative records were retrospectively reviewed with emphasis on tumor recurrence and survival. Statistical analysis was performed using Kaplan-Meier analysis. The mean followup for the laparoscopy group was 40.4 +/- 18.0 months. A total of 83 patients survived. Of these patients 2 patients experienced disease recurrence within 18 to 46.2 months, 1 patient died of cancer metastasis to brain within 29.7 months and 1 died of an unrelated cause. Seeding of the port sites did not develop in any of the patients. The 5-year disease-free and actuarial survival rates for this group were 91.4%, and 93.8%, respectively. The 58 patients who underwent open surgery had a mean followup of 49.68 +/- 28.84 months. A total of 53 patients survived without any disease recurrence, 1 survived with recurrence within 8 months, 1 survived with metastasis within 49 months and 3 died of unrelated causes. The 5-year disease-free and patient survival rates for this group were 97.6% and 95.8%, respectively. Kaplan-Meier disease-free survival and patient survival analysis revealed no significant differences between the laparoscopic and open partial nephrectomy groups. Laparoscopic partial nephrectomy is an alternative technique with mid-range oncological results comparable to open partial nephrectomy in patients with localized pathological stage T1N0M0 renal cell carcinoma.Keywords
This publication has 18 references indexed in Scilit:
- EXPLORING THE LEARNING CURVE, PATHOLOGICAL OUTCOMES AND PERIOPERATIVE MORBIDITY OF LAPAROSCOPIC PARTIAL NEPHRECTOMY PERFORMED FOR RENAL MASSJournal of Urology, 2005
- Laparoscopic partial nephrectomy: evaluation of long-term oncological outcome: Allaf ME, Bhayani SB, Rogers C, Varkarakis I, Link RE, Inagaki T, Jarrett TW, Kavoussi LR, Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MDUrologic Oncology: Seminars and Original Investigations, 2005
- Laparoscopic and Partial NephrectomyClinical Cancer Research, 2004
- LAPAROSCOPIC PARTIAL NEPHRECTOMY: EVALUATION OF LONG-TERM ONCOLOGICAL OUTCOMEJournal of Urology, 2004
- Laparoscopic Radical versus Partial Nephrectomy: Assessment of ComplicationsJournal of Urology, 2003
- Comparative Analysis of Laparoscopic Versus Open Partial Nephrectomy for Renal Tumors in 200 PatientsJournal of Urology, 2003
- Nephron-sparing surgery for localized renal cell carcinoma with a normal contralateral kidney: a European three-center experienceUrology, 2002
- Matched Comparison of Radical Nephrectomy vs Nephron-Sparing Surgery in Patients With Unilateral Renal Cell Carcinoma and a Normal Contralateral KidneyMayo Clinic Proceedings, 2000
- LONG-TERM RESULTS OF NEPHRON SPARING SURGERY FOR LOCALIZED RENAL CELL CARCINOMA: 10-YEAR FOLLOWUPJournal of Urology, 2000
- Laparoscopic Wedge Resection of a Renal Tumor: Initial ExperienceJournal of Laparoendoscopic Surgery, 1993