Inter‐ and intrasubject variability of gastric emptying in healthy volunteers measured by scintigraphy and paracetamol absorption.
Open Access
- 1 June 1990
- journal article
- research article
- Published by Wiley in British Journal of Clinical Pharmacology
- Vol. 29 (6), 703-708
- https://doi.org/10.1111/j.1365-2125.1990.tb03691.x
Abstract
1. Inter- and intrasubject variability in the gastric emptying of semisolids and liquids was measured by scintigraphic emptying of radionuclide-labelled semisolid and from paracetamol absorption in ten healthy volunteers of both sexes. 2. The intrasubject variability was not statistically significant for any of scintigraphic or paracetamol absorption parameters. 3. The intersubject variation was significant for all scintigraphic and paracetamol absorption parameters. 4. In women, the gastric emptying rate of semisolid decreased linearly during the menstrual cycle. 5. The lag period and paracetamol absorption parameters were unrelated to the day of the menstrual cycle day. 6. There was no statistically significant relationship between scintigraphic and paracetamol absorption parameters.This publication has 18 references indexed in Scilit:
- The effect of phentolamine on basal and pethidine‐induced inhibition of gastric emptying in healthy volunteers.British Journal of Clinical Pharmacology, 1989
- Proximal, distal and total stomach emptying of a digestible solid meal in normal subjectsThe British Journal of Radiology, 1988
- Effect of the Menstrual Cycle on Gastric EmptyingDigestion, 1987
- The relationship between gastric emptying of semisolids and paracetamol absorption.British Journal of Clinical Pharmacology, 1986
- Variability of gastric emptying measurements in man employing standardized radiolabeled mealsDigestive Diseases and Sciences, 1986
- The normal menstrual cycle has no effect on gastric emptyingBJOG: An International Journal of Obstetrics and Gynaecology, 1985
- Changes in Gastric Emptying Rates with AgeClinical Science, 1984
- EFFECT OF ANAESTHESIA ON GASTRIC MOTILITY AND EMPTYINGBritish Journal of Anaesthesia, 1984
- Gastric emptying in normal subjects--a reproducible technique using a single scintillation camera and computer system.Gut, 1983
- Kinetics of acetaminophen absorption and gastric emptying in manCancer Cell, 1978