Action of Imipramine and Amitriptyline on Cerebral Monoamines as Compared with Chlorpromazine
- 1 January 1962
- journal article
- research article
- Published by S. Karger AG in Pharmacology
- Vol. 6 (3), 165-168
- https://doi.org/10.1159/000135152
Abstract
In rat brain, imipramine and amitriptyline are less potent than chlorpromazine in counteracting the 5HT increase due to iproniazid as well as the 5HT and NE decrease due to reserpine in vivo. Similar results are obtained regarding the 5HTP-induced 5HT increase in vivo and post mortem.Keywords
This publication has 2 references indexed in Scilit:
- INFLUENCE OF CHLORPROMAZINE AND CHLORPROTHIXENE ON CEREBRAL METABOLISM OF 5-HYDROXYTRYPTAMINE, NOREPINEPHRINE AND DOPAMINE1961
- THE 5‐HYDROXYTRYPTAMINE CONTENT OF MOUSE BRAIN AND WHOLE MICE AFTER TREATMENT WITH SOME DRUGS AFFECTING THE CENTRAL NERVOUS SYSTEMBritish Journal of Pharmacology and Chemotherapy, 1960